Melissa Gomezstaff Writer, Los Angeles Times, 27 Dec. Marisa Sloan, Discover Magazine, 21 July 2021 Two-thirds of the state is mountainous, creating a mosaic of remote villages like my mother’s. 2022 With the right cocktail of extreme heat and pressure, any remaining gaps will be filled by other atomic shapes to produce a quasiperiodic pattern that'sreminiscent of a three-dimensional mosaic. 2023 The replica head emerges from the ground floor into a room above, which is decorated with a golden mosaic on the walls and a starry ceiling. PMID 22561519.Noun Happiness is made up of a mosaic of all these small moments. "Detectable clonal mosaicism and its relationship to aging and cancer". Somatic mosaicism in healthy human tissues. "X Inactivation in females with X-linked disease". ↑ Curt Stern described the set-up as "functional mosaicism".The epigenetics revolution, how modern biology is rewriting our understanding of genetics, disease and inheritance. ↑ An account suitable for biology students is given in Carey, Nessa 2012."Epigenetic dynamics of imprinted X inactivation during early mouse development". Harvard University Press, Cambridge, Massachusetts. Somatic crossing-over and segregation in Drosophila melanogaster. ↑ The term has also been used for organisms with cells derived from more than one zygote.Cancer research has shown that somatic mutations are responsible for most leukemia, lymphomas, and solid tumors. Somatic mutation leading to mosaicism is common in the beginning and end stages of human life. Mutations in body cells (somatic mutations) cause groups of cells to differ in their genetics. This may give rise to mild symptoms in female 'carriers' of X-linked genetic disorders. Descendent cells of the embryo carry the same X-inactivation as the original cells. X-inactivation is an epigenetic change, a switching off of genes on one chromosome. X-inactivation causes groups of cells to carry either one or the other X-chromosome in an active state. These females are heterozygous for the X-linked colour genes: the genes for their coat colours are carried on the X chromosome. This phenomenon shows in the colouration of calico cats and tortoiseshell cats. X-inactivation is reversed in the female germline, so that all egg cells contain an active X chromosome. This inactivation lasts the lifetime of the cell, and all the descendants of the cell inactivate that same chromosome. In the early embryo, each cell independently and randomly inactivates one copy of the X chromosome. They have the same genes, but at some loci (positions) they may have different alleles (versions of the same gene). The two X chromosomes in a female are rarely identical. Females have two X chromosomes (and males have only one). This is a controlled and natural developmental phenomenon in mammalian females. On this page, only genetic mosaicism is discussed. For example, David Bowie has the appearance of different eye colours due to an injury that caused one pupil to be permanently dilated. It can have many different causes, both genetic and accidental. When eye colours vary between the two eyes, or within one or both eyes, the condition is called heterochromia iridis (= 'different coloured iris'). A mosaic is originally from a single fertilised egg, whereas a chimaera comes from two fertilised eggs. People who have mosaicism are often called chimeras but this is a mistake. These are organisms which contain two or more genetically distinct types of tissue. When it does, it results in somatic (body) mosaics. In 1936, he demonstrated that recombination, normal in meiosis, can also take place in mitosis. The phenomenon was discovered by Curt Stern. X-inactivation: one X chromosome is randomly switched off in cells of a female mammal.A chromosomal mutation during development.As a result, the individual has two or more genetically different cell lines derived from a single zygote.
In genetics, a mosaic (or mosaicism) means the presence of two different genotypes in an individual which developed from a single fertilized egg.
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